The Interstitium, A New Human Organ Discovery… The Hydration Organ

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The Interstitium, A New Human Organ Discovery…

The Hydration Organ

Doctors and research scientists announced the discovery of the interstitium. It is described as now the largest organ of the human body. This hydration organ is like a highway for water transportation under the skin, around muscles and other organs. The more we learn about the critical role of hydration in the human body the more evident is our need for both biologically clean and energetically clean (or balanced) water for optimum hydration and wellness. This type of water is known as Aqua Tune Water. This is water that has been structured and infused with beneficial frequency blends with Tuning Element’s Bio Energetic Alignment Technology B.E.A.T.TM.

Feinstein Institute researcher defines a part of the body as an organ

Feinstein Institute for Medical Research researcher Petros Constantinos Benias, MD, and collaborators have identified that layers of the body long thought to be dense, connective tissues are actually interconnected, fluid-filled compartments, categorizing this part of the body as an organ. This discovery, published today in Scientific Reports, could lead to better understanding and improved treatments for cancer and other inflammatory conditions.”

“For years we have known that more than half the fluid in the body is within cells, and approximately a seventh of the fluid is inside the heart, blood vessels, lymph nodes, and lymph vessels – the remaining fluid is “interstitial.” The interstitium, or connective tissue, up to now, has been thought mostly to exist between cells defined historically as a “third space”, but this does not account for the massive amount of fluid stored within the human body outside of the vascular system. Occasionally the concept that there is a larger interstitial space has been generally referred to, though its anatomic or histologic features have never been described. The Scientific Reports paper is the first to define the interstitium as an organ and as one of the largest in the body. The interstitium is a series of spaces, supported by a meshwork of strong and flexible connective tissue proteins found below the skin’s surface, lining the digestive tract, lungs and urinary systems, and surrounding arteries, veins, and the fascia between muscles. In the digestive tract, for example, the entire submucosal space or layer of the stomach lining has been redefined by this work as a complex interstitium that communicates with the lymphatic system. This space moves fluid throughout the body and is the source of lymph, a fluid in the body that aids immune cells that generate inflammation. Researchers involved in this study believe this could explain why cancer that invades this interstitial space becomes much more likely to spread. The researchers also found that the cells in the interstitium change with age, which may contribute to the wrinkling of skin, the stiffening of limbs, and the progression of fibrotic, sclerotic and inflammatory diseases.”


Part of the reason why researchers were able to make this discovery is the progression of technology. Historically, tissue has been fixed and studied by way of a conventional microscope. This process dramatically alters the structure of the tissue and artificially collapses the interstitium. The research team, instead of using traditional microscopes to examine the interstitium used cutting-edge technology- Probe-based confocal laser endomicroscopy which allows human tissue to be examined on a cellular level, live at the time of endoscopy. Dr. Benias collaborated with Mount Sinai Beth Israel Medical Center, NYU School of Medicine, and the University of Pennsylvania. This work was funded in part by a National Institutes of Health grant (DK081523).

About the Feinstein Institute

The Feinstein Institute for Medical Research is the research arm of Northwell Health, the largest healthcare provider in New York. Home to 50 research laboratories and to clinical research throughout dozens of hospitals and outpatient facilities, the Feinstein Institute includes 4,000 researchers and staff who are making breakthroughs in molecular medicine, genetics, oncology, brain research, mental health, autoimmunity, and bioelectronic medicine – a new field of science that has the potential to revolutionize medicine. For more information about how we empower imagination and pioneer discovery, visit